Discovery of functional variants regulating lipid metabolism in an East Asian population
Sungji Moon, Young Jun Park, Jaeyong Choi, Jeong Mi Kim, Su Hyeon Yi, Minji Kim, Juyoung Lee, Juhyun Kim, Ho-Young Son, Jong-Il Kim, Sun-Wha Im
Metabolism
Single-cell time-course transcriptomic analysis reveals epithelial remodeling in human gastric corpus organoids after WNT pathway perturbation
Na-Yeon Kim, Seung-Pyo Hong, Dakyung Lee, Kyunghyuk Park, Bukyoung Cha, Taekyung Lee, Jong-Il Kim
Organoid
The Gain-of-Function GLP1R R131Q Variant Preserves β-Cell Function and Enhances Response to GLP-1 Receptor Agonists
Hyunsuk Lee, Hannah E. Christie, Ji Seon Lee, Woo-Il Kwon, Min Kyong Moon, Sung Hee Choi, Dae Ho Lee, Seunggeun Lee, Hyunbeom Lee, Minjung Kho, Federica Boscolo, Chiara Dalla Man, Nam H. Cho, Jaewon Choi, Jeongeun Lee, Jongseok Park, Yeeun Jo, Sangwon Lee, Adrian Vella, Soo Heon Kwak, Jong-Il Kim, Kyong Soo Park
Diabetes Care
Epithelial plasticity in lung cancer evolution: insights from organoids
Sungji Moon, Dakyung Lee, Jaeyong Choi, Seyoon Lee, Jong-Il Kim
Organoid
Polygenic risk score refines cardiovascular disease risk in individuals with type 2 diabetes at borderline or intermediate risk
Jaewon Choi, Hyunsuk Lee, Tae-Min Rhee, Jun-Bean Park, Soo Heon Kwak
Journal of Diabetes Investigation
구순구개열과 IRF6과 MSX 유전자의 단일염기다형성과의 연관성: 타액 유래 DNA를 활용한 예비 연구
장유정, 박영준, 백승학, 이헌진, 김종일, 홍미희
Korean Journal of Cleft Lip and Palate
Rare variant optimized GWAS with functional validation identifies causal architecture of kidney function in East Asian population
Jiyun Jang, Jaeyong Choi, Sungji Moon, Jeong Mi Kim, Jong-Il Kim, Sun-Wha Im
Scientific Reports
Micro-scale control of oligodendrocyte morphology and myelination by the intellectual disability-linked protein acyltransferase ZDHHC9
Hey-Kyeong Jeong, Estibaliz Gonzalez-Fernandez, Ilan Crawley, Julia M Coakley, Jinha Hwang, Dale D O Martin, Shernaz X Bamji, Jong-Il Kim, Shin H Kang, Gareth M Thomas
Elife
A Tumor-Promoting Inflammatory SPP1⁺ Macrophage–IL6–CRP Axis Drives Immune Dysfunction in Bladder Cancer
Michelle A. Tran, Byuri Angela Cho, Sudeh Izadmehr, Seong-Keun Yoo, Dina Youssef, Jonathan F. Anker, Adam M. Farkas, Igor Figueiredo, Karen Lee, Aparna Ananthanarayanan, Sreekumar Balan, Sayali Onkar, Romain Banchereau, Saurabh Gupta, Aparna Chhibber, Li Wang, Kristin G. Beaumont, Ziao Li, Monica Garcia-Barros, Mesude Bicak, Carlos Cordon-Cardo, Rachel Brody, Seunghee Kim-Schulze, Kobe Yuen, Sanjeev Mariathasan, Saad O. Atiq, Tolulope T. Adeyelu, Andrew Elliott, Pedro Barata, Rana R. McKay, Sacha Gnjatic, Edgar Gonzalez-Kozlova, Reza Mehrazin, Amir Horowitz, John P. Sfakianos, Diego Chowell, Matthew D. Galsky, Nina Bhardwaj
Cancer Discovery
Salary and Support Continuity Influence Medical Students’ Intentions to Pursue Physician-Scientist Careers: Results of an Experimental Survey
Moo Hyuk Lee, Jong-Il Kim, Young Kyung Do
Journal of Korean Medical Science
PAX4 R192H variant impairs β cell function by disrupting β cell identity and compensatory capacity in response to metabolic stress
Jungsun Park, Kyun Hoo Kim, Hyunsuk Lee, Joon Ho Moon, Soo Heon Kwak, Jong Il Kim, Hail Kim, Kyong Soo Park
Genome Medicine
Genetic and Lifestyle Factors Influence High 1-Hour Plasma Glucose, a Predictor of Type 2 Diabetes Mellitus
Soobin Cho, Hyunsuk Lee, Joon Ha, Yeonsoo Park, Joon Ho Moon, Hak Chul Jang, Kyong Soo Park, Nam H. Cho, Michael Bergman, Soo Heon Kwak
Diabetes & Metabolism Journal
A multi-omic single-cell landscape of perinatal mouse skin maps lineage specification and reveals shared dynamics in human fetal skin
Hanjae Lee, Seunghee Lee, Seong Jin Jo, Sunhyoung Lee, Hyunjung Go, Ohsang Kwon, Jong-Il Kim
Experimental & Molecular Medicine
Immunopathogenic role of the HLA-B∗51:01-specific immunopeptidome in Behçet's disease
Yeji Lee, Kyung-Cho Cho, Byoung-Kyu Cho, So Hyun Kim, Jun Won Park, Dongjin Shin, Jong-Il Kim, Insoo Kang, Eugene C. Yi, Eun Bong Lee
Journal of Autoimmunity
A genome-wide interaction study of thyroid-stimulating hormone levels and particulate matter exposure among Koreans
Young Jun Park, Hyun-Jin Kim, Ho-Young Son, Juhyun Kim, Jae Moon Yun, Hyuktae Kwon, Belong Cho, Jin-Ho Park, Jong-Il Kim
Genes and Environment
Directed differentiation of human mesenchymal stromal cells into functional endothelial cells having IKAROS-mediated immune tolerance properties
Jung-Kyu Han, Haena Lee, Dasom Shin, Youngchul Shin, HanJun Oh, Seyoon Lee, Seong Keun Kwon, Minseop Kim, Ju-Hee Kim, Seok Chung, Jong-Il Kim, Hyo-Soo Kim
Biomaterials
Single-cell and spatial transcriptomics unveil myeloid–lymphoid cross talk and the dermal immune niche underlying palmoplantar pustulosis
Hanjae Lee, Juyoung Lee, Hyeok Ahn, Kyunghyuk Park, Bukyung Cha, Cheol Lee, Ohsang Kwon, Seong Jin Jo, Jong-Il Kim
Journal of Allergy and Clinical Immunology
Therapeutic Potential of Heat Shock Protein 90 Inhibitor 17-DMAG in Regulating METTL3 for Kidney Fibrosis Treatment
Soo Min Lee, Myoung Seok Lee, Hae Rim Jung, Jeonghwan Lee, Bogyeong Cho, Wencheng Jin, Min Hoan Moon, Nayeon Shin, Seung Hyun Han, Da Som Choi, Bada Lee, Seung-Pyo Hong, Jong-Il Kim, Chun Soo Lim, Sung-Yup Cho, Jin Woo Choi, Jung Pyo Lee
Journal of the American Society of Nephrology
Mitochondrial-encoded peptide MOTS-c prevents pancreatic islet cell senescence to delay diabetes
Byungsoo Kong, Hyunsuk Lee, Serin Hong, Young Min Cho
Experimental & Molecular Medicine
Peripheral blood transcriptome signatures indicate environmental influences in monozygotic twins discordant for Alzheimer's disease
Jee Hoon Roh, Chanhyeok Park, Suhyun Kim, Jong-Yeon Shin, Jong-Il Kim, Young-Wook Yoon, Kun-Woo Park, Thor D Stein, Junghee Lee, Jae-Hong Lee, Hoon Ryu
Biochim Biophys Acta Mol Basis Dis.
Association of high-dose radioactive iodine therapy with PPM1D-mutated clonal hematopoiesis in older individuals
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun-Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul-Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong-Il Kim
Molecular Oncology
Anti-Senescence Effect of Inhibiting Sodium-Glucose Cotransporter 2 and α-Glucosidase in a Type 2 Diabetes Animal Model
Serin Hong, Byungsoo Kong, Hyunsuk Lee, Young Min Cho
Diabetes & Metabolism Journal
It Is Time for Physician-Scientists to Lead Their Own Development
Dong Hyeon Lee & Jong-Il Kim
Journal of Korean Medical Science
Type 1 interferon signature and allograft inflammatory factor-1 contribute to refractoriness to TNF inhibition in ankylosing spondylitis
Woogil Song, Eunyoung Emily Lee, Seongwan Park, Baekgyu Choi, Min-Gang Kim, Seo Yoon Ban, Se Rim Choi, Jeong Yeon Kim, Seon Uk Kim, Jong-Il Kim, Eui-Cheol Shin, Inkyung Jung, Jeong Seok Lee, Eun Young Lee & theSingle-Cell Atlas of Immune Diseases Consortium
Nature Communications
Exploring the shared genetic landscape of diabetes and cardiovascular disease: findings and future implications (Review)
Hyunsuk Lee, Maria Fernandes, Jeongeun Lee, Jordi Merino, Soo Heon Kwak
Diabetologia
Physician-Scientist Training System and Development Strategies in Korea
Gwang Hyeon Eom, Jungmin Kim, Jong-Il Kim, Hyo Yi Choi & Dong Hyeon Lee
Journal of Korean Medical Science
Harnessing institutionally developed clinical targeted sequencing to improve patient survival in breast cancer: a seven-year experience
Jiwon Koh, Jinyong Kim, Go-Un Woo, Hanbaek Yi, So Yean Kwon, Jeongmin Seo, Jeong Mo Bae, Jung Ho Kim, Jae Kyung Won, Han Suk Ryu, Yoon Kyung Jeon, Dae-Won Lee, Miso Kim, Tae-Yong Kim, Kyung-Hun Lee, Tae-You Kim, Jee-Soo Lee, Moon-Woo Seong, Sheehyun Kim, Sungyoung Lee, Hongseok Yun, Myung Geun Song, Jaeyong Choi, Jong-Il Kim, Seock-Ah Im
Cancer Research and Treatment
Real-time continuous glucose monitoring improves postoperative glucose control in people with type 2 diabetes mellitus undergoing coronary artery bypass grafting: A randomized clinical trial
Heejun Son, Suk Ho Sohn, Hyun Ah Kim, Hun Jee Choe, Hyunsuk Lee, Hye Seung Jung, Young Min Cho, Kyong Soo Park, Ho Young Hwang, Soo Heon Kwak
Diabetes Obesity and Metabolism
Assembly of glioblastoma tumoroids and cerebral organoids: a 3D in vitro model for tumor cell invasion
Jieun Kim, Rokhyun Kim, Wonseok Lee, Gyu Hyun Kim, Kyung Hyun Kim, Woochan Lee, Kyunghyuk Park, Sun-Wha Im, Kea Joo Lee, Chul-Kee Park, Jong-Il Kim, Ji Yeoun Lee
Molecular Oncology
Neuroplasticity therapy using glia-like cells derived from human mesenchymal stem cells for the recovery of cerebral infarction sequelae
Eun-Ji Lee, Min-Ju Lee, Sehyeon Song, Rokhyun Kim, Ye-Jin Ryu, Jeongyeon Min, Kyunghyuk Park, Young Jun Park, Jong-Il Kim, Mi-Sook Chang, Seong-Ho Koh
Molecular Therapy
Genomic Profiling of Intimal Sarcoma Reveals Molecular Subtypes with Distinct Tumor Microenvironments and Therapeutic Implications
Changhee Park, Rokhyun Kim, Jeongmo Bae, Jaeyong Choi,
Taebum Lee, Sanghoon Song, Jeonghwan Youk, Miso Kim,
Bhumsuk Keam, Tae Min Kim, Jong-Il Kim, Dong-Wan Kim
ESMO Open
Simultaneous Epigenetic and Gene Expression Profiling at Single Cell Resolution Uncovers Stem-Like Treg Subsets Induced With Oligonucleotide Expansion in Humans
Hyo Jeong Nam, Jeong-Ryeol Gong, Yong-Hee Kim, Thuy Nguyen-Phuong, Nari Byun, Jeong Heon Yoon, Yong Chan Kim, Hyunwoo Chung, Brian Hyohyoung Lee, Haeyoon Kwon, Woochan Lee, Sung-Jun Kang, Kyunghyuk Park, Bukyoung Cha, Jong-Il Kim & Hyun Je Kim
Immune Network
Genetic and Epigenetic Alterations in Aging and Rejuvenation of Human
Kyunghyuk Park,Min Chul Jeon; Dakyung Lee; Jong-Il Kim; Sun-Wha Im
Molecules and Cells
Differentiating Visceral Sensory Ganglion Organoids from Induced Pluripotent Stem Cells
Kyusik Ahn, Hwee-Seon Park, Sieun Choi, Hojeong Lee, Hyunjung Choi, Seok Beom Hong, Jihui Han, Jong Won Han, Jinchul Ahn, Jaehoon Song, Kyunghyuk Park, Bukyung Cha, Minseop Kim, Hui-Wen Liu, Hyeonggyu Song, Sang Jeong Kim, Seok Chung, Jong-Il Kim, Inhee Mook-Jung
Nature Methods
Discrepancy Between Genetically-Predicted and Observed Body Mass Index Predicts Incident Type 2 Diabetes Mellitus
Tae-Min Rhee, Jaewon Choi, Hyunsuk Lee, Jordi Merino, Jun-Bean Park, Soo Heon Kwak
Diabetes Care
Identification of New Pathogenic Variants of Hereditary Diffuse Gastric Cancer
Seung-Young Oh, Giyong Jang, Jaeryuk Kim, Kyoung-Yun Jeong, Hyun Myong Kim, Yoon Jin Kwak, Seong-Ho Kong, Do Joong Park, Hyuk-Joon Lee, Sung-Yup Cho, Jong-Il Kim & Han-Kwang Yang
Cancer Research and Treatment
Image-based deep learning model using DNA methylation data predicts the origin of cancer of unknown primary
Hwang Jinha, Yeajina Lee, Seong-Keun Yoo, Jong-Il Kim
Neoplasia
Genome-Wide Polygenic Risk Score Predicts Incident Type 2 Diabetes in Women with History of Gestational Diabetes
Jaewon Choi, Hyunsuk Lee, Alan Kuang, Alicia Huerta-Chagoya, Denise M. Scholtens, Daeho Choi, Minseok Han, William L. Lowe Jr., Alisa K. Manning, Hak Chul Jang, Kyong Soo Park, Soo Heon Kwak
Diabetes Care
Microglia Gravitate toward Amyloid Plaques Surrounded by Externalized Phosphatidylserine via TREM2
Jong-Chan Park, Jong Won Han, Woochan Lee, Jieun Kim, Sang-Eun Lee, Dongjoon Lee, Hayoung Choi, Jihui Han, You Jung Kang, Yen N Diep, Hansang Cho, Rian Kang, Won Jong Yu, Jean Lee, Murim Choi, Sun-Wha Im, Jong-Il Kim & Inhee Mook-Jung
Adv Sci (Weinh)
Blockade of STING activation rescues microglia dysfunction and a broad spectrum of Alzheimer’s disease pathologies
Sunwoo Chung, June-Hyun Jeong , Jong-Chan Park, Jong Won Han, Yeajina Lee, Jong-Il Kim, Inhee Mook-Jung
Experimental & Molecular Medicine
Higher Genetic Risk for Type 2 Diabetes Is Associated with a Faster Decline of Beta Cell Function in an East Asian Population
Hyunsuk Lee, Jaewon Choi, Jong-Il Kim, Richard M. Watanabe, Nam H Cho, Kyong Soo Park, and Soo Heon Kwak
Diabetes Care
Genome-wide association study for metabolic syndrome reveals APOA5 single nucleotide polymorphisms with multilayered effects in Koreans
Young Jun Park, Sungji Moon, Jaeyong Choi, Juhyun Kim, Hyun-Jin Kim, Ho-Young Son, Sun-Wha Im, Jong-Il Kim
Lipids in Health and Disease
Risk of pulmonary embolism and deep vein thrombosis following COVID-19: a nationwide cohort study
Hye Jun Kim, Seogsong Jeong, Jihun Song, Sun Jae Park, Young Jun Park, Yun Hwan Oh, Jaehun Jung, Sang Min Park
MedComm
The New Era of JAK Inhibitors: Impelling Updates in Alopecia Areata Guideline
Hanjae Lee, Sang Hyun Park, Bark-Lynn Lew, Hyunsun Park
Journal of the European Academy of Dermatology and Venereology
Single-Cell and Spatial Transcriptome Analysis of Dermal Fibroblast Development in Perinatal Mouse Skin: Dynamic Lineage Differentiation and Key Driver Genes
Hanjae Lee, Soyoung Kim, Nak-Jung Kwon, Seong Jin Jo, Ohsang Kwon, Jong-Il Kim
Journal of Investigative Dermatology
Antibiotic exposure and depression incidence: A cohort study of the Korean population
Jaewon Lee, Sun Jae Park, Seulggie Choi, Jooyoung Chang, Young Jun Park, Seogsong Jeong, Joung Sik Son, Gyeongsil Lee, Joseph C. Ahn, Jihoon Andrew Kim, Sang Min Park
Psychiatry Research
RNA expression of 6 genes from metastatic mucosal gastric cancer serves as the global prognostic marker for gastric cancer with functional validation
Yun-Suhk Suh, Jieun Lee, Joshy George, Donghyeok Seol, Kyoungyun Jeong, Seung-Young Oh, Chanmi Bang, Yukyung Jun, Seong-Ho Kong, Hyuk-Joon Lee, Jong-Il Kim, Woo Ho Kim, Han-Kwang Yang & Charles Lee
British Journal of Cancer
Association between antibiotic use and subsequent risk of prostate cancer: A retrospective cohort study in South Korea
Sun Jae Park, Jaeyi Hong, Young Jun Park, Seogsong Jeong, Seulggie Choi, Jooyoung Chang, Yun Hwan Oh, Minjung Han, Ahryoung Ko, Sugyeong Kim, Yoosun Cho, Ji Soo Kim, Joung Sik Son, Sang Min Park
International Journal of Urology
Exploring the role of apolipoprotein E gene promoter polymorphisms in the susceptibility to normal-tension glaucoma in a Korean population
Young Jun Park, Hye-Young Shin, Jong-Il Kim
Scientific Reports
Case series of soft tissue sarcoma patients with brain metastasis with implications from genomic and transcriptomic analysis
Changhee Park, Rokhyun Kim, Jaeyong Choi, Miso Kim, Tae Min Kim, Ilkyu Han, Jong-Il Kim, Han-Soo Kim
Cancer Research and Treatment
Central neurocytoma exhibits radial glial cell signatures with FGFR3 hypomethylation and overexpression
Yeajina Lee, Tamrin Chowdhury, Sojin Kim, Hyeon Jong Yu, Kyung-Min Kim, Ho Kang, Min-Sung Kim, Jin Wook Kim, Yong-Hwy Kim, So Young Ji, Kihwan Hwang, Jung Ho Han, Jinha Hwang, Seong-Keun Yoo, Kyu Sang Lee, Gheeyoung Choe, Jae-Kyung Won, Sung-Hye Park, Yong Kyu Lee, Joo Heon Shin, Chul-Kee Park, Chae-Yong Kim, Jong-Il Kim
Experimental & Molecular Medicine
Placental Expression Quantitative Trait Loci In An East Asian Population
Jaeyong Choi, Seung Mi Lee, Errol R. Norwitz, Ji Hoi Kim, Young Mi Jung, Chan-Wook Park, Jong Kwan Jun, Dakyung Lee, Sookyung Kim, Bukyoung Cha, Joong Shin Park, and Jong-Il Kim
HGG Advances
Brain hypothyroidism silences the immune response of microglia in Alzheimer's disease animal model
Dong Kyu Kim, Hyunjung Choi, Woochan Lee, Hayoung Choi, Seok Beom Hong, June-Hyun Jeong, Jihui Han, Jong Won Han, Hoon Ryu, Jong-Il Kim & Inhee Mook-Jung
Science Advances
The Clinical relevance of Polygenic Risk Scores to Type 2 Diabetes Mellitus in Korean Population
Seunggeun Lee; Na Yeon Kim; Haekyung Lee; Sehee Kim; Ye-Jee Kim; Hyunsuk Lee; Junyheong Lee; Soo Heon Kwak
Scientific Reports
Potential Perturbations of Critical Cancer-regulatory Genes in Triple-Negative Breast Cancer Cells Within the Humanized Microenvironment of Patient-derived Xenograft Models
Yujeong Her, Jihui Yun, Hye-Youn Son, Woohang Heo, Jong-Il Kim, Hyeong-Gon Moon
Journal of Breast Cancer
Targeting the m(6)A RNA methyltransferase METTL3 attenuates the development of kidney fibrosis.
Hae Rim Jung, Jeonghwan Lee, Seung-Pyo Hong, Nayeon Shin, Ara Cho, Dong-Jin Shin, Jin Woo Choi, Jong-Il Kim, Jung Pyo Lee & Sung-Yup Cho
Experimental & Molecular Medicine
Association Between Antibiotic Exposure and Thyroid Cancer: A Nationwide Cohort Study in South Korea
Sun Jae Park, Minseo Kim, Seogsong Jeong, Young Jun Park, Seulggie Choi, Jooyoung Chang, Yun Hwan Oh, Sun Wook Cho, Young Joo Park, Sang Min Park
Thyroid
Genetic studies of actinic keratosis development: Where are we now?
Jong-Il Kim, Young Bok Lee
Annals of Dermatology
Profiling of Microbial Landscape in Lung of Chronic Obstructive Pulmonary Disease Patients using RNA sequencing
Dongjin Shin,Juhyun Kim,Jang Ho Lee, Yeon-Mok Oh & Jong-Il Kim
International Journal of Chronic Obstructive Pulmonary Disease
Association between antibiotics and asthma risk among adults aged over 40 years: a nationally representative retrospective cohort study
Jiwon Choi, Sun Jae Park, Young Jun Park, Jaeyi Hong, Seogsong Jeong, Jooyoung Chang, Sung Min Kim, Jihun Song, Yoosun Cho, Sang Min Park
BMJ Open Respiratory Research
Multidimensional fragmentomic profiling of cell-free DNA released from patient-derived organoids
"Jaeryuk Kim, Seung-Pyo Hong, Seyoon Lee, Woochan Lee, Dakyung Lee, Rokhyun Kim, Young Jun Park, Sungji Moon, Kyunghyuk Park, Bukyoung Cha, Jong-Il Kim
"
Human Genomics
Subclinical articulatory changes of vowel parameters in Korean amyotrophic lateral sclerosis patients with perceptually normal voices
Jin-Ah Kim ,Hayeun Jang ,Yoonji Choi,Young Gi Min,Yoon-Ho Hong,Jung-Joon Sung ,Seok-Jin Choi
PLOS ONE
Long-term antibiotic use and risk of hepatocellular carcinoma later in life: a nationwide cohort study of 9.8 million participants
Seogsong Jeong, Sun Jae Park, Minseo Kim, Young Jun Park, Seulggie Choi, Jooyoung Chang, Ji Soo Kim, Yun Hwan Oh, Ahryoung Ko, Sang Min Park
Cancer Communications
Tagmentation-based analysis reveals the clonal behavior of CAR-T cells in association with lentivector integration sites
Jaeryuk Kim, Miyoung Park, Gyungwon Baek, Joo-Il Kim, Euna Kwon, Byeong-Cheol Kang, Jong-Il Kim, Hyoung Jin Kang
Molecular Therapy - Oncolytics
"Association of phosphorylated pyruvate dehydrogenase with pyruvate kinase M2 promotes PKM2 stability in response to insulin"
"Abu Jubayer Hossain, Rokibul Islam, Jong-Bok Seo, Hwee-Seon Park, Jong-Il Kim, Vikas Kumar, Keun
Woo Lee, Jae-Bong Park"
International Journal of Molecular Sciences
A single cell atlas of in vitro multi-systems uncovers in vivo lineage trajectory and cell state in the human lung
Woochan Lee, Seyoon Lee, Jung-Ki Yoon, Dakyung Lee, Yuri Kim, Yeon Bi Han, Rokhyun Kim, Sungji Moon, Young Jun Park, Kyunghyuk Park, Bukyoung Cha, Jaeyong Choi, Juhyun Kim, Na-young Ha, Kwhanmien Kim, Sukki Cho, Nam-Hyuk Cho, Tushar J. Desai, Jin-Haeng Chung, Joo-Hyeon Lee, Jong-Il Kim
Experimental & Molecular Medicine
A genome-wide by PM10 exposure interaction study for blood pressure in Korean adults
Hyun-Jin Kim, Ho-Young Son, Jae Moon Yun, Hyuktae Kwon, Belong Cho, Jong-Il Kim, and Jin-Ho Park
Scientific Reports
A whole-genome reference panel of 14,393 individuals for East Asian populations accelerates discovery of rare functional variants
Jaeyong Choi, Sungjae Kim, Juhyun Kim, Ho-Young Son, Seong-Keun Yoo, Chang-Uk Kim, Young Jun Park, Sungji Moon, Bukyoung Cha, Min Chul Jeon, Kyunghyuk Park, Jae Moon Yun, Belong Cho, Namcheol Kim, Changhoon Kim, Nak-Jung Kwon, Young Joo Park, Fumihiko Matsuda, Yukihide Momozawa, Michiaki Kubo, The Biobank Japan Project, Hyun-Jin Kim, Jin-Ho Park, Jeong-Sun Seo, Jong-Il Kim, and Sun-Wha Im
Science Advances
Triple-negative breast cancer-derived extracellular vesicles promote a hepatic pre-metastatic niche via a cascade of microenvironment remodeling
Woohang Heo, Woochan Lee, Jong Ho Cheun, Eun-Shin Lee, Songbin Li, Hoe suk Kim, Hye-Youn Son, Ju Hee Kim, Yeon Duk Woo, Doo Hyun Chung, Jihui Yun, Ji Gwang Jung, Han-Byoel Lee, Wonshik Han, Hong-Kyu Kim, Jong-Il Kim, Hyeong-Gon Moon
Molecular Cancer Research
Smoking cessation after diagnosis of COPD is associated with lower all-cause and cause-specific mortality: a nationwide population-based cohort study of South Korean men
Jang Ho Doo, Sung Min Kim, Young Jun Park, Kyae Hyung Kim, Yun Hwan Oh, Ji Soo Kim, Sang Min Park
BMC Pulmonary Medicine
Association of antibiotic use with risk of lung cancer: A nationwide cohort study
Minseo Kim, Sun Jae Park, Seulggie Choi, Seogsong Jeong, Jooyoung Chang, Young Jun Park, Joung Sik Son, Ji Soo Kim, Yoosun Cho, Yun Hwan Oh, Ahryoung Ko, Sang Min Park
Journal of Infection and Public Health
Direct Differentiation of Bone Marrow Mononucleated Cells Into Insulin-Producing Cells Using 4 Specific Soluble Factors
Seung-Ah Lee, Subin Kim, Seog-Young Kim, Jong Yoen Park, Jinyan Nan, Ho Seon Park, Hyunsuk Lee, Yong Deok Lee, Hakmo Lee, Shinae Kang, Hye Seung Jung, Sung Soo Chung, Kyong Soo Park
Stem Cells Translational Medicine
Earlier Age at Type 2 Diabetes Diagnosis Is Associated with Increased Genetic Risk for Cardiovascular Disease
Hyunsuk Lee, Jaewon Choi, Na Yeon Kim, Jong-Il Kim, Min Kyong Moon, Seunggeun Lee, Kyong Soo Park and Soo Heon Kwak
Diabetes Care
Small RNA Sequencing of Circulating Small Extracellular Vesicles MicroRNAs in Patients with Amyotrophic Lateral Sclerosis
Jin-Ah Kim, Canaria Park, Jung-Joon Sung, Do-Jin Seo, Seok-Jin Choi, Yoon-Ho Hong
Scientific Reports
Novel genetic variants associated with chronic kidney disease progression
Miyeun Han, Sungji Moon, Sangjun Lee, Kyungsik Kim, Woo Ju An, Hyunjin Ryu, Eunjeong Kang, Jung-Hyuck Ahn, Hye Youn Sung, Yong Seek Park, Seung Eun Lee, Sang-Ho Lee, Kyung Hwan Jeong, Curie Ahn, Tanika N. Kelly, Jesse Y. Hsu, Harold I. Feldman, Sue K. Park, Kook-Hwan Oh
Journal of the American Society of Nephrology
Genomic analysis as a tool to infer disparate phylogenetic origins of dysembryoplastic neuroepithelial tumors and their satellite lesions
Yeajina Lee, Jeyul Yang, Seung Ah Choi, Seung‐Ki Kim, Sung-Hye Park, Hyun Joo Park, Jong-Il Kim, and Ji Hoon Phi
Scientific Reports
An integrative approach for exploring the nature of fibroepithelial neoplasms
Jihui Yun, Woohang Heo, Eun-Shin Lee, Deukchae Na, Wonyoung Kang, Jinjoo Kang, Jeesoo Chae, Dakyung Lee, Woochan Lee, Jinha Hwang, Tae-Kyung Yoo, Bok Sil Hong, Hye-Youn Son, Dong-Young Noh, Charles Lee, Hyeong-Gon Moon, Jong-Il Kim
British Journal of Cancer
Different effects of low muscle mass on the risk of non-alcoholic fatty liver disease and hepatic fibrosis in a prospective cohort
Hun Jee Choe, Hyunsuk Lee, Dong Ho Lee, Soo-Heon Kwak, Bo Kyung Koo
Journal of Cachexia, Sarcopenia and Muscle
Long-Term Effect of PNPLA3 on the Aggravation of Nonalcoholic Fatty Liver Disease in the Biopsy-Proven Cohort
Bo Kyung Koo, Hyunsuk Lee, Soo-Heon Kwak, Dong Hyeon Lee, Jeong Hwan Park, Won Kim, Innovative Target Exploration of NAFLD (ITEN) consortium
Clinical Gastroenterology and Hepatology
Immune checkpoint inhibitor-induced cutaneous toxicities: they are not just random.
Hanjae Lee & Ohsang Kwon
British Journal of Dermatology (commentary)
Early onset female pattern hair loss: A case-control study for analyzing clinical features and genetic variants
김종일,Ohn Jungyoon,Son Ho-Young,Yu Da-Ae,Kim Min Su,Kwon Sijin,Park Won-Seok,권오상
JOURNAL OF DERMATOLOGICAL SCIENCE
A glioneuronal tumor with CLIP2-MET fusion.
Chowdhury T, Lee Y, Kim S, Yu HJ, Ji SY, Bae JM, Won JK, Shin JH, Weinberger DR, Choi SH, Park CK, Kim JI, Park SH
NPJ Genomic Medicine
Effects of tamoxifen and aromatase inhibitors on the risk of acute coronary syndrome in elderly breast cancer patients: An analysis of nationwide data.
Choi SH, Kim KE, Park Y, Ju YW, Jung JG, Lee ES, Lee HB, Han W, Noh DY, Yoon HJ, Moon HG
Breast
Phase II study of durvalumab and tremelimumab in pulmonary sarcomatoid carcinoma: KCSG-LU16-07
Kim M, Keam B, Ock CY, Kim SH, Kim YJ, Lim SM, Kim JS, Kim TM, Hong SH, Ahn MS, Shin SH, Kang EJ, Kim DW, Im SW, Kim JI, Lee JS, Kim JH, Heo DS
Thoracic Cancer
A High Quality Asian Genome Assembly Identifies Features of Common Missing Regions
Kim J, Sung J, Han K, Lee W, Mun S, Lee J, Bahk K, Yang I, Bae YK, Kim C, Kim JI, Seo JS
Genes (Basel)
Treatment strategy for papillary renal cell carcinoma type 2: a case series of seven patients treated based on next generation sequencing data.
Ji-Yeon Kim, Hyoung-Oh Jeong, Dae Seog Heo, Bhumsuk Keam, Kyung Chul Moon, Cheol Kwak, Jinho Jang, Seunghoon Kim, Jong-Il Kim, Semin Lee, Se-Hoon Lee
Annals of Translational Medicine
An Essential Role of the N-Terminal Region of ACSL1 in Linking Free Fatty Acids to Mitochondrial beta-Oxidation in C2C12 Myotubes
Jinyan Nan, Ji Seon Lee, Seung-Ah Lee, Dong-Sup Lee, Kyong Soo Park, Sung Soo Chung
Molecules and Cells
CRISPR screens identify a novel combination treatment targeting BCL-X-L and WNT signaling for KRAS/BRAF-mutated colorectal cancers
Hae Rim Jung, Yumi Oh, Deukchae Na, Seoyeon Min, Jinjoo Kang, Dongjun Jang, Seungjae Shin, Jiwon Kim, Sang Eun Lee, Eui Man Jeong, Joon Yong An, Chang Ohk Sung, Won-Suk Lee, Charles Lee, Sung-Yup Cho
Oncogene
Discovery of acquired molecular signature on immune checkpoint inhibitors in paired tumor tissues
Shin Hye Yoo #, Jihui Yun #, Bhumsuk Keam, Seung-Pyo Hong, Chan-Young Ock, Jaemoon Koh, Sehui Kim, Yoon Kyung Jeon, Kyeong Cheon Jung, Miso Kim, Tae Min Kim, Dong-Wan Kim, Jong-Il Kim, Dae Seog Heo
CANCER IMMUNOLOGY IMMUNOTHERAPY
Effects of Intermittent Fasting on the Circulating Levels and Circadian Rhythms of Hormones
Bo Hye Kim, Yena Joo, Min-Seon Kim, Han Kyoung Choe, Qingchun Tong, Obin Kwon
Endocrinology and Metabolism
HSP90 protects apoptotic cleavage of vimentin in geldanamycin-induced apoptosis
Mei-Hua Zhang, Jae-Seon Lee, Hee-Jung Kim, Dong-Il Jin, Jong-Il Kim, Kong-Joo Lee, Jeong-Sun Seo
Molecular and Cellular Biochemistry
Intestinal protozoan infections and echinococcosis in the inhabitants of Dornod and Selenge, Mongolia (2003)
Sun Huh, Jae-Ran Yu, Jong-Il Kim, Choijamts Gotov, Radnaabazar Janchiv, Jeong-Sun Seo
the Korean Journal of Parasitology
The role of tonicity responsive enhancer sites in the transcriptional regulation of human hsp70-2 in response to hypertonic stress
Jee In Heo, Mi Suk Lee, Jeong Hyun Kim, Jae Seon Lee, Jaebong Kim, Jae Bong Park, Jae Yong Lee, Jeong A Han, Jong Il Kim
Experimental and Molecular Medicine
Genome-wide combination profiling of copy number and methylation offers an approach for deciphering misregulation and development in cancer cells
Jung Jun Park, Jae Ku Kang, Su Hong, Eun Sook Ryu, Jong-Il Kim, Jong Ho Lee, Jeong-Sun Seo
Gene
Heritability and linkage study on heart rates in a Mongolian population
Bayasgalan Gombojav, Hansoo Park, Jong Il Kim, Young Seok Ju, Joohon Sung, Sung Il Cho, Mi Kyeong Lee, Heechoul Ohrr, Janchiv Radnaabazar, Jeong Sun Seo
Experimental and Molecular Medicine
A genome-wide Asian genetic map and ethnic comparison: the GENDISCAN study
Young Seok Ju, Hansoo Park, Mi-Kyeong Lee, Jong-Il Kim, Joohon Sung, Sung-Il Cho, Jeong-Sun Seo
BMC Genomics
Higher mitochondrial DNA copy number is associated with lower prevalence of microalbuminuria
Jung Eun Lee, Hansoo Park, Young Seok Ju, Minhye Kwak, Jong Il Kim, Ha Young Oh, Jeong Sun Seo
Experimental and Molecular Medicine
A highly annotated whole-genome sequence of a Korean individual
Jong-Il Kim, Young Seok Ju, Hansoo Park, Sheehyun Kim, Seonwook Lee, Jae-Hyuk Yi, Joann Mudge, Neil A Miller, Dongwan Hong, Callum J Bell, Hye-Sun Kim, In-Soon Chung, Woo-Chung Lee, Ji-Sun Lee, Seung-Hyun Seo, Ji-Young Yun, Hyun Nyun Woo, Heewook Lee, Dongwhan Suh, Seungbok Lee, Hyun-Jin Kim, Maryam Yavartanoo, Minhye Kwak, Ying Zheng, Mi Kyeong Lee, Hyunjun Park, Jeong Yeon Kim, Omer Gokcumen, Ryan E Mills, Alexander Wait Zaranek, Joseph Thakuria, Xiaodi Wu, Ryan W Kim, Jim J Huntley, Shujun Luo, Gary P Schroth, Thomas D Wu, HyeRan Kim, Kap-Seok Yang, Woong-Yang Park, Hyungtae Kim, George M Church, Charles Lee, Stephen F Kingsmore, Jeong-Sun Seo
Nature
Analysis of genetic and non-genetic factors that affect the QTc interval in a Mongolian population: the GENDISCAN study
Sun-Wha Im, Mi Kyeong Lee, Hee Jeong Lee, Se-Il Oh, Hyung-Lae Kim, Joohon Sung, Sung-Il Cho, Jeong-Sun Seo, Jong-Il Kim
Experimental and Molecular Medicine
Research Highlights: Interrogation of allele-specific gene expression by a digital RNA allelotyping method using padlock-captured SNPs from the transcriptome of human cell lines
Jae-Hyuk Yi, Jong-Ii Kim, Jeong-Sun Seo
Personalized Medicine
Discovery of common Asian copy number variants using integrated high-resolution array CGH and massively parallel DNA sequencing
Hansoo Park, Jong-Il Kim, Young Seok Ju, Omer Gokcumen, Ryan E Mills, Sheehyun Kim, Seungbok Lee, Dongwhan Suh, Dongwan Hong, Hyunseok Peter Kang, Yun Joo Yoo, Jong-Yeon Shin, Hyun-Jin Kim, Maryam Yavartanoo, Young Wha Chang, Jung-Sook Ha, Wilson Chong, Ga-Ram Hwang, Katayoon Darvishi, Hyeran Kim, Song Ju Yang, Kap-Seok Yang, Hyungtae Kim, Matthew E Hurles, Stephen W Scherer, Nigel P Carter, Chris Tyler-Smith, Charles Lee, Jeong-Sun Seo
Nature Genetics
Reference-unbiased copy number variant analysis using CGH microarrays
Young Seok Ju, Dongwan Hong, Sheehyun Kim, Sung-Soo Park, Sujung Kim, Seungbok Lee, Hansoo Park, Jong-Il Kim, Jeong-Sun Seo
Nucleic Acids Research
The first Irish genome and ways of improving sequence accuracy
Young Seok Ju, Yun Joo Yoo, Jong-Il Kim, Jeong-Sun Seo
Genome Biology
Genome-wide linkage analysis for ocular and nasal anthropometric traits in a Mongolian population
Sun-Wha Im, Hyun-Jin Kim, Mi Kyeong Lee, Jae-hyuk Yi, Ganchimeg Jargal, Joohon Sung, Sung-il Cho, Jong-Il Kim
Experimental and Molecular Medicine
Extensive genomic and transcriptional diversity identified through massively parallel DNA and RNA sequencing of eighteen Korean individuals
Young Seok Ju, Jong-Il Kim, Sheehyun Kim, Dongwan Hong, Hansoo Park, Jong-Yeon Shin, Seungbok Lee, Won-Chul Lee, Sujung Kim, Saet-Byeol Yu, Sung-Soo Park, Seung-Hyun Seo, Ji-Young Yun, Hyun-Jin Kim, Dong-Sung Lee, Maryam Yavartanoo, Hyunseok Peter Kang, Omer Gokcumen, Diddahally R Govindaraju, Jung Hee Jung, Hyonyong Chong, Kap-Seok Yang, Hyungtae Kim, Charles Lee, Jeong-Sun Seo
Nature Genetics
Genetic diagnosis of Duchenne and Becker muscular dystrophy using next-generation sequencing technology: comprehensive mutational search in a single platform
Byung Chan Lim 1 , Seungbok Lee, Jong-Yeon Shin, Jong-Il Kim, Hee Hwang, Ki Joong Kim, Yong Seung Hwang, Jeong-Sun Seo, Jong Hee Chae
Journal of Medical Genetics
https://pubmed.ncbi.nlm.nih.gov/22110370
Jaeho Yoon, Jung-Ho Kim, Ok-Joo Lee, Saet-Byeol Yu, Jong-Il Kim, Sung Chan Kim, Jae-Bong Park, Jae-Yong Lee, Jaebong Kim
Experimental Neurobiology
Linkage and association scan for tanning ability in an isolated Mongolian population
Seung Hwan Paik, Hyun-Jin Kim, Seungbok Lee, Sun-Wha Im, Young Seok Ju, Je Ho Yeon, Seong Jin Jo, Hee Chul Eun, Jeong-Sun Seo, Jong-Il Kim, Oh Sang Kwon
BMB Reports
A transforming KIF5B and RET gene fusion in lung adenocarcinoma revealed from whole-genome and transcriptome sequencing
Young Seok Ju, Won-Chul Lee, Jong-Yeon Shin, Seungbok Lee, Thomas Bleazard, Jae-Kyung Won, Young Tae Kim, Jong-Il Kim, Jin-Hyoung Kang, Jeong-Sun Seo
Genome Research
Gene mapping study for constitutive skin color in an isolated Mongolian population
Seung Hwan Paik, Hyun-Jin Kim, Ho-Young Son, Seungbok Lee, Sun-Wha Im, Young Seok Ju, Je Ho Yeon, Seong Jin Jo, Hee Chul Eun, Jeong-Sun Seo, Oh Sang Kwon, Jong-Il Kim
Experimental and Molecular Medicine
Epidemiologic characteristics of intraocular pressure in the Korean and Mongolian populations: the Healthy Twin and the GENDISCAN study
Mi Kyeong Lee, Sung-Il Cho, Ho Kim, Yun-Mi Song, Kayoung Lee, Jong-Il Kim, Dong-Myung Kim, Tae-Young Chung, Youn Sic Kim, Jeong-Sun Seo, Don-Il Ham, Joohon Sung
Ophthalmology
FX: an RNA-Seq analysis tool on the cloud
Dongwan Hong, Arang Rhie, Sung-Soo Park, Jongkeun Lee, Young Seok Ju, Sujung Kim, Saet-Byeol Yu, Thomas Bleazard, Hyun-Seok Park, Hwanseok Rhee, Hyonyong Chong, Kap-Seok Yang, Yeon-Su Lee, In-Hoo Kim, Jin Soo Lee, Jong-Il Kim, Jeong-Sun Seo
Bioinformatics
RNA-Seq analysis of frontal cortex and cerebellum from 5XFAD mice at early stage of disease pathology
Kyung Hwa Kim, Minho Moon, Saet-Byeol Yu, Inhee Mook-Jung, Jong-Il Kim
Journal of Alzheimer's disease
A public resource facilitating clinical use of genomes
Madeleine P Ball, Joseph V Thakuria, Alexander Wait Zaranek, Tom Clegg, Abraham M Rosenbaum, Xiaodi Wu, Misha Angrist, Jong Bhak, Jason Bobe, Matthew J Callow, Carlos Cano, Michael F Chou, Wendy K Chung, Shawn M Douglas, Preston W Estep, Athurva Gore, Peter Hulick, Alberto Labarga, Je-Hyuk Lee, Jeantine E Lunshof, Byung Chul Kim, Jong-Il Kim, Zhe Li, Michael F Murray, Geoffrey B Nilsen, Brock A Peters, Anugraha M Raman, Hugh Y Rienhoff, Kimberly Robasky, Matthew T Wheeler, Ward Vandewege, Daniel B Vorhaus, Joyce L Yang, Luhan Yang, John Aach, Euan A Ashley, Radoje Drmanac, Seong-Jin Kim, Jin Billy Li, Leonid Peshkin, Christine E Seidman, Jeong-Sun Seo, Kun Zhang, Heidi L Rehm, George M Church
PNAS
The transcriptional landscape and mutational profile of lung adenocarcinoma
Jeong-Sun Seo, Young Seok Ju, Won-Chul Lee, Jong-Yeon Shin, June Koo Lee, Thomas Bleazard, Junho Lee, Yoo Jin Jung, Jung-Oh Kim, Jung-Young Shin, Saet-Byeol Yu, Jihye Kim, Eung-Ryoung Lee, Chang-Hyun Kang, In-Kyu Park, Hwanseok Rhee, Se-Hoon Lee, Jong-Il Kim, Jin-Hyoung Kang, Young Tae Kim
Genetics Research
Comprehensive genomic analyses associate UGT8 variants with musical ability in a Mongolian population
Hansoo Park, Seungbok Lee, Hyun-Jin Kim, Young Seok Ju, Jong-Yeon Shin, Dongwan Hong, Marcin von Grotthuss, Dong-Sung Lee, Changho Park, Jennifer Hayeon Kim, Boram Kim, Yun Joo Yoo, Sung-Il Cho, Joohon Sung, Charles Lee, Jong-Il Kim, Jeong-Sun Seo
Journal of Medical Genetics
A family-based association study after genome-wide linkage analysis identified two genetic loci for renal function in a Mongolian population
Hansoo Park, Hyun-Jin Kim, Seungbok Lee, Yun Joo Yoo, Young Seok Ju, Jung Eun Lee, Sung-Il Cho, Joohon Sung, Jong-Il Kim, Jeong-Sun Seo
Kidney International
Exomic sequencing of immune-related genes reveals novel candidate variants associated with alopecia universalis
Seungbok Lee, Seung Hwan Paik, Hyun-Jin Kim, Hyeong Ho Ryu, Soeun Cha, Seong Jin Jo, Hee Chul Eun, Jeong-Sun Seo, Jong-Il Kim, Oh Sang Kwon
PLos One
Copy number variation of age-related macular degeneration relevant genes in the Korean population
Jung Hyun Park, Seungbok Lee, Hyeong Gon Yu, Jong-Il Kim, Jeong-Sun Seo
PLos One
Molecular diagnosis of congenital muscular dystrophies with defective glycosylation of alpha-dystroglycan using next-generation sequencing technology
Byung Chan Lim, Seungbok Lee, Jong-Yeon Shin, Hee Hwang, Ki Joong Kim, Yong Seung Hwang, Jeong-Sun Seo, Jong-Il Kim, Jong Hee Chae
Neuromuscular Disorders
Epigenetic regulation of cholinergic receptor M1 (CHRM1) by histone H3K9me3 impairs Ca(2+) signaling in Huntington's disease
Junghee Lee, Yu Jin Hwang, Jong-Yeon Shin, Won-Chul Lee, Jinhong Wie, Ki Yoon Kim, Min Young Lee, Daehee Hwang, Rajiv R Ratan, Ae Nim Pae, Neil W Kowall, Insuk So, Jong-Il Kim, Hoon Ryu
Acta Neuropathologica
TIARA genome database: update 2013
Dongwan Hong, Jongkeun Lee, Thomas Bleazard, HyunChul Jung, Young Seok Ju, Saet-byeol Yu, Sujung Kim, Sung-Soo Park, Jong-Il Kim, Jeong-Sun Seo
Database (OXford)
Primary resistance to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) in patients with non-small-cell lung cancer harboring TKI-sensitive EGFR mutations: an exploratory study
J K Lee, J-Y Shin, S Kim, S Lee, C Park, J-Y Kim, Y Koh, B Keam, H S Min, T M Kim, Y-K Jeon, D-W Kim, D H Chung, D S Heo, S-H Lee, J-I Kim
Annals of Oncology
Copy number variation of age-related macular degeneration relevant genes in the Korean population
Jung Hyun Park, Seungbok Lee, Hyeong Gon Yu, Jong-Il Kim, Jeong-Sun Seo
PLoS One
Combined linkage and association analyses identify a novel locus for obesity near PROX1 in Asians
Hyun-Jin Kim, Yun Joo Yoo, Young Seok Ju, Seungbok Lee, Sung-Il Cho, Joohon Sung, Jong-Il Kim, Jeong-Sun Seo
Obesity
Heritabilities of facial measurements and their latent factors in korean families
Hyun-Jin Kim, Sun-Wha Im, Ganchimeg Jargal, Siwoo Lee, Jae-Hyuk Yi, Jeong-Yeon Park, Joohon Sung, Sung-Il Cho, Jong-Yeol Kim, Jong-Il Kim, Jeong-Sun Seo
Genomics and Informatics
Targeted resequencing of candidate genes reveals novel variants associated with severe Behçet's uveitis
Sang Jin Kim, Seungbok Lee, Changho Park, Jeong-Sun Seo, Jong-Il Kim, Hyeong Gon Yu
Experimental and Molecular Medicine
Gene expression profiling by mRNA sequencing reveals increased expression of immune/inflammation-related genes in the hippocampus of individuals with schizophrenia
Hwang Y, Kim J, Shin JY, Kim JI, Seo JS, Webster MJ, Lee D, Kim S
Translational Psychiatry
A multifunctional protein EWS regulates the expression of Drosha and microRNAs
K Y Kim, Y J Hwang, M-K Jung, J Choe, Y Kim, S Kim, C-J Lee, H Ahn, J Lee, N W Kowall, Y K Kim, J-I Kim, S B Lee, H Ryu
Cell Death and Differentiation
Novel fusion transcripts in human gastric cancer revealed by transcriptome analysis
H-P Kim, G-A Cho, S-W Han, J-Y Shin, E-G Jeong, S-H Song, W-C Lee, K-H Lee, D Bang, J-S Seo, J-Il Kim, T-Y Kim
Oncogene
Somatic deletions implicated in functional diversity of brain cells of individuals with schizophrenia and unaffected controls
Junho Kim, Jong-Yeon Shin, Jong-Il Kim, Jeong-Sun Seo, Maree J Webster, Doheon Lee, Sanghyeon Kim
Scientific Reports
A role of placental growth factor in hair growth
Sun-Young Yoon, Ji-Seon Yoon, Seong Jin Jo, Chang Yup Shin, Jong-Yeon Shin, Jong-Il Kim, Ohsang Kwon, Kyu Han Kim
Journal of Dermatological Science
RANBP2-ALK fusion combined with monosomy 7 in acute myelomonocytic leukemia
Ji-Hun Lim, Seongsoo Jang, Chan-Jeoung Park, Young-Uk Cho, Je-Hwan Lee, Kyoo-Hyung Lee, Jin-Ok Lee, Jong-Yeon Shin, Jong-Il Kim, Jooryung Huh, Eul-Ju Seo
Cancer Genetics
RNA editing in RHOQ promotes invasion potential in colorectal cancer
Sae-Won Han, Hwang-Phill Kim, Jong-Yeon Shin, Eun-Goo Jeong, Won-Chul Lee, Keon Young Kim, Sang Youn Park, Dae-Won Lee, Jae-Kyung Won, Seung-Yong Jeong, Kyu Joo Park, Jae-Gahb Park, Gyeong Hoon Kang, Jeong-Sun Seo, Jong-Il Kim, Tae-You Kim
Journal of Experimental Medicine
Engineered prime editors with PAM flexibility
Jiyeon Kweon, Jung-Ki Yoon, An-Hee Jang, Ha Rim Shin, Ji-Eun See, Gayoung Jang, Jong-Il Kim, Yongsub Kim
Molecular Therapy
Genomic profile of metastatic breast cancer patient-derived xenografts established using percutaneous biopsy
Seongyeong Kim, Dongjin Shin, Ahrum Min, Minjung Kim, Deukchae Na, Han-Byeol Lee, Han Suk Ryu, Yaewon Yang, Go-Un Woo, Kyung-Hun Lee, Dae-Won Lee, Tae-Yong Kim, Charles Lee, Seock-Ah Im & Jong-Il Kim
Journal of Translational Medicine
High prevalence of TP53 loss and whole-genome doubling in early-onset colorectal cancer
Jeong Eun Kim, Jaeyong Choi, Chang-Ohk Sung, Yong Sang Hong, Sun Young Kim, Hyunjung Lee, Tae Won Kim & Jong-Il Kim
Experimental & Molecular Medicine
Image Correlation-Based Method to Assess Ciliary Beat Frequency in Human Airway Organoids
Woo June Choi; Jung-Ki Yoon; Bjorn Paulson; Chang-Hoon Lee; Jae-Joon Yim; Jong-Il Kim; Jun Ki Kim
IEEE Transactions on Medical Imaging
Intensity of metastasis screening and survival outcomes in patients with breast cancer
Jong-Ho Cheun, Jigwang Jung, Eun-Shin Lee, Jiyoung Rhu, Han-Byoel Lee, Kyung-Hun Lee, Tae-Yong Kim, Wonshink Han, Seock-Ah Im, Dong-Young Noh & Hyeong-Gon Moon
Scientific Reports
JAK2 regulates paclitaxel resistance in triple negative breast cancers
Jongmin Han, Jihui Yun, Mingji Quan, Wonyoung Kang, Ji-Gwang Jung, Woohang Heo, Songbin Li, Kyu Jin Lee, Hye-Youn Son, Ju Hee Kim, Jaeyong Choi, Dong-Young Noh, Deukchae Na, Han Suk Ryu, Charles Lee, Jong-Il Kim & Hyeong-Gon Moon
Journal of Molecular Medicine
NTRK and RET fusion–directed therapy in pediatric thyroid cancer yields a tumor response and radioiodine uptake
Young Ah Lee, Hyunjung Lee, Sun-Wha Im, Young Shin Song, Do-Youn Oh, Hyoung Jin Kang, Jae-Kyung Won, Kyeong Cheon Jung, Dohee Kwon, Eun-Jae Chung, J. Hun Hah, Jin Chul Paeng, Ji-hoon Kim, Jaeyong Choi, Ok-Hee Kim, Ji Min Oh, Byeong-Cheol Ahn, Lori J. Wirth, Choong Ho Shin, Jong-Il Kim, and Young Joo Park
The Journal of Clinical Investigation
Predictive biomarkers for 5-fluorouracil and oxaliplatin-based chemotherapy in gastric cancers via profiling of patient-derived xenografts
Deukchae Na, Jeesoo Chae, Sung-Yup Cho, Wonyoung Kang, Ahra Lee, Seoyeon Min, Jinjoo Kang, Min Jung Kim, Jaeyong Choi, Woochan Lee, Dongjin Shin, Ahrum Min, Yu-Jin Kim, Kyung-Hun Lee, Tae-Yong Kim, Yun-Suhk Suh, Seong-Ho Kong, Hyuk-Joon Lee, Woo-Ho Kim, Hansoo Park, Seock-Ah Im, Han-Kwang Yang, Charles Lee & Jong-Il Kim
Nature Communications
S100A8/A9 mediate the reprograming of normal mammary epithelial cells induced by dynamic cell–cell interactions with adjacent breast cancer cells
Seol Hwa Jo, Woo Hang Heo, Hye-Youn Son, Mingji Quan, Bok Sil Hong, Ju Hee Kim, Han-Byoel Lee, Wonshik Han, Yeonju Park, Dong-Sup Lee, Nam Hoon Kwon, Min Chul Park, Jeesoo Chae, Jong-Il Kim, Dong-Young Noh & Hyeong-Gon Moon
Scientific Reports
Sequencing Cell-free Fetal DNA in Pregnant Women With GCK-MODY
Soo Heon Kwak, Camille E Powe, Se Song Jang, Michael J Callahan, Sarah N Bernstein, Seung Mi Lee, Sunyoung Kang, Kyong Soo Park, Hak C Jang, Jose C Florez, Jong-Il Kim, Jong Hee Chae
The Journal of Clinical Endocrinology & Metabolism
Targeting antioxidant enzymes enhances the therapeutic efficacy of the BCL-X-L inhibitor ABT-263 in KRAS-mutant colorectal cancers
Yumi Oh, Hae Rim Jung, Seoyeon Min, Jinjoo Kang, Dongjun Jang, Seungjae Shin, Jiwon Kim, Sang Eun Lee, Chang Ohk Sung, Won-Suk Lee, Charles Lee, Eui Man Jeong, Sung-Yup Cho
Cancer Letters
Vertical sleeve gastrectomy induces distinctive transcriptomic responses in liver, fat and muscle
Chang Ho Ahn, Eun Hye Choi, Hyunjung Lee, Woochan Lee, Jong-Il Kim & Young Min Cho
Scientific Reports
Early-onset female pattern hair loss: a case–control study for analyzing clinical features and genetic variants
Jungyoon Ohn, Ho-Young Son, Da-Ye Yu, Min Su Kim, Sijin Kwon, Won-Seok Park, Ohsang Kwon, and Jong-Il Kim
Journal of Dermatological Science
Experimental development of the epigenomic library construction method to elucidate the epigenetic diversity and causal relationship between epigenome and transcriptome at a single-cell level
Kyunghyuk Park, Min Chul Jeon, Bokyung Kim, Bukyoung Cha, Jong-Il Kim
Genomics and Informatics
Deconvolution of Adult T-Cell Leukemia/Lymphoma With Single-Cell RNA-SeqUsing Frozen Archived Skin Tissue Reveals New Subset of Cancer-Associated Fibroblast
Eun-Hye Joo, Jai Hee Bae, Jihye Park, Yoon Ji Bang, Joseph Han, Nicholas Gulati, Jong-Il Kim, Chung-Gyu Park, Woong-Yang Park, Hyun Je Kim
Frontiers in Immunology
Thyroid nodules in childhood-onset Hashimoto's thyroiditis: Frequency, risk factors, follow-up course and genetic alterations of thyroid cancer
Yun Jeong Lee,Yeon Jin Cho,You Joung Heo,Eun-Jae Chung,Young Hun Choi,Jong-Il Kim,Young Joo Park,Choong Ho Shin,Young Ah Lee
Clinical Endocrinology
A genome-wide association study identifies COL4A1-COL4A2 as a susceptibility locus for visceral adiposity in adult Korean men
Hyun-Jin Kim, Ho-young Son, Joohon Sung, Jae Moon Yun, Hyuktae Kwon, Belong Cho, Jong-Il Kim, and Jin-Ho Park
Obesity Facts
Expression-based species deconvolution and realignment removes misalignment error in multispecies single-cell data
Jaeyong Choi, Woochan Lee, Jung-Ki Yoon, Sun Mi Choi, Chang-Hoon Lee, Hyeong-Gon Moon, Sukki Cho, Jin-Haeng Chung, Han-Kwang Yang, Jong Il Kim
BMC Bioinformatics
Cross-talk between Wnt signaling and Src tyrosine kinase
Jung Ki Min, Hwee-Seon Park, Yoon-Beom Lee, Jae-Gyu Kim, Jong-Il Kim, Jae-Bong Park
Biomedicines
Mitochondrial dysfunction-induced KDM5A degradation impairs adult hippocampal neurogenesis in Alzheimer’s disease
Dong Kyu Kim, Hyobin Jeong, Jingi Bae, Moon-Yong Cha, Moonkyung Kang, Dongjin Shin, Shinwon Ha, Seung Jae Hyeon, Hokeun Kim, Kyujin Suh, Mi-Sun Choi, Hoon Ryu, Seong-Woon Yu, Jong-Il Kim, Yeon-Soo Kim, Sang-Won Lee, Daehee Hwang, Inhee MookJung
Experimental & Molecular Medicine
